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Product Overview
Product Name Rhein
CAS478-43-3
FormulaC15H8O6
MW284.22
Appearance 橙黃色粉末
Melting point321-321.5 °C (sublm)
Boiling point597.8±50.0 °C | Condition: Press: 760 Torr
PKa3.17±0.20 | Condition: Most Acidic Temp: 25 °C
Product details

WKQ-0000151

中文名稱:大黃酸

中文別名:1,8-二羥基-3-羧基蒽醌;4,5-二羥蒽醌-2-羧酸;4,5-二羥基-9,10-二氧-9,10-二氫蒽-2-羧酸

英文名稱:Rhein

英文別名:2-Anthraquinonecarboxylic acid, 4,5-dihydroxy- (6CI);2-Anthroic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo- (8CI);9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid;1,8-Dihydroxy-3-carboxyanthraquinone;1,8-Dihydroxyanthraquinone-3-carboxylic acid;4,5-Dihydroxy-2-anthraquinonecarboxylic acid;Cassic acid;Chrysazin-3-carboxylic acid;Monorhein;NSC 38629;Rheic acid;Rhein;Rheinic acid;Rhubarb yellow;

分子式:C15H8O6

分子量:284.22

CAS號(hào):478-43-3

純度:HPLC≥98%

熔點(diǎn):321-321.5 °C (sublm)

沸點(diǎn):597.8±50.0 °C | Condition: Press: 760 Torr

密度:1.687±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr

酸系度數(shù):3.17±0.20 | Condition: Most Acidic Temp: 25 °C

儲(chǔ)存條件:-20℃,干燥、避光、密封

規(guī)格:5mg10mg20mg50mg100mg500mg1g2g等應(yīng)客戶需求包裝

供應(yīng)單位:四川省維克奇生物科技有限公司

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Related literature
Sanhuang Xiexin decoction ameliorates DSS-induced colitis in mice by regulating intestinal inflammation, intestinal barrier, and intestinal flora
Source:SCI:JOURNAL OF ETHNOPHARMACOLOGY Author:Xueyuan Wu Notes:影響因子:5.195
Reference description

All the medicinal materials were tested, and their quality met the relevant standards of the 2020 edition of the Chinese Pharmacopoeia. Standard reference compounds, including epiberberine (wkq20031807), coptisine (wkq20021306), palmatine (wkq20051201), berberine (wkq20032408), baicalin (wkq20010908), wogonoside (wkq20040108), baicalein (wkq20022608), wogonin (20030204), rhein (wkq20052209), aloe-emodin (wkq20032708), emodin (wkq20041308), chrysophanol (wkq20081705), and physcion (wkq20040101) were purchased from Weikeqi Biotechnology Co., Ltd (Chengdu, China). The purity of all standard products was higher than 98%. Chromatographic grade acetonitrile and formic acid were purchased from Thermo-Fisher (US).

Pharmacokinetic comparisons of major bioactive components after oral administration of raw and steamed rhubarb by UPLC-MS/MS
Source:SCI:JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS Author:Jing Zhang Notes:影響因子:2.983
Reference description

All the chemicals were from commercial sources and were analytical reagent or above. Aloe-emodin (110795–201308), emodin (110756–200110), and physcion (110758–200912) were purchased from National Institutes for Food and Drug Control (Beijing, China). Rhein (wkq17062803) was purchased from Sichuan Weikeqi Biological Technology Co. Ltd (Sichuan, China). Daidzein (MUST-16022713) used as internal standards (IS), was obtained from Chengdu Must Bio-Technology Co. Ltd (Chengdu, China).

Comprehensive Quantitative Analysis of 32 Chemical Ingredients of a Chinese Patented Drug Sanhuang Tablet
Source:SCI:MOLECULES Author:Hau-Yee Fung Notes:影響因子:2.861
Reference description

Reference standards of (1) loganic acid (Lot no. 131220); (5) scutellarin (130306); (8) apigetrin (130315); (11) baicalin (121128); (12) eriodictyol (130606); (13) quercetin (131120); (14) scutellarein (131219); (15) oroxyloside (121122); (17) wogonoside (131214); (18) baicalein (130119); (19) aloe-emodin (130425); (21) wogonin (140521) and (23) oroxylin A (130323) were provided by Chengdu Preferred Biotechnology Co. Ltd. (Chengdu, China). Reference compounds of (3) daidzin (131214); (4) sennoside B (130409); (6) luteoloside (130418); (7) sennoside A (130306); (9) rhaponticin (140604); (10) daidzein (130715); (16) physcion (140211); (20) rhein (131024); (22) chrysophanol (140219); (24) emodin (140422); (25) coptisine (130628); (26) epiberberine (130621); (27) jatrorrhizine hydrochloride (130318); (28) palmatine hydrochloride (130702) and (29) berberine hydrochloride (140314) were provided by Sichuan Weikeqi Biological Technology Co., Ltd. (Chengdu, China). Reference marker of (2) caffeic acid (130428) was provided by Chengdu Herbpurify Co., Ltd. (Chengdu, China).

Chemical profiling and quantification of ShenKang injection, a systematic quality control strategy using ultra high performance liquid chromatography with Q Exactive hybrid quadrupole orbitrap high-resolution accurate mass spectrometry
Source:SCI:JOURNAL OF SEPARATION SCIENCE Author:Tanye Xu Notes:影響因子:2.557
Reference description

SK injection samples were manufactured by Xi'an Shi Ji Sheng Kang Pharmaceutical industry (Xi'an, China). The samples were diluted by four times to inject. The reference standards aloe-emodin, rhein, emodin, chrysophanol, physcion and astragaloside IV were purchased from Chengdu Weikeqi Bio-technology (Sichuan, China). Gallic acid, chlorogenic acid, caffeic acid, ferulic acid, rosmarinic acid, ethyl ferulate, protocatechuic acid, protocatechu aldehyde, catechin, hydroxysafflor yellow A

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