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Chicoric acid

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Product Overview
Product Name Chicoric acid
CAS70831-56-0
FormulaC22H18O12
MW474.37
Melting point206 °C
Boiling point46-47 °C
PKa1.42±0.25 | Condition: Most Acidic Temp: 25 °C
Product details

WKQ-0030239

中文名稱:菊苣酸

英文名稱:Chicoric acid

英文別名:Butanedioic acid, 2,3-bis[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-, (2R,3R)- (9CI);Butanedioic acid, 2,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-, [R-[R*,R*-(E,E)]]-;(2R,3R)-2,3-Bis[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]butanedioic acid;(-)-Chicoric acid;(-)-L-Chicoric acid;Chicoric acid, (-)-;L-Chicoric acid;NSC 99173;l-Chicoric acid;trans-Caffeoyltartaric acid;

分子式:C22H18O12

分子量:474.37

CAS號(hào):70831-56-0

純度:HPLC≥98%

熔點(diǎn):206 °C

沸點(diǎn):46-47 °C

密度:1.641±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr

酸系度數(shù):1.42±0.25 | Condition: Most Acidic Temp: 25 °C

儲(chǔ)存條件:-20℃,干燥、避光、密封

規(guī)格:5mg10mg20mg50mg100mg500mg1g2g等應(yīng)客戶需求包裝

供應(yīng)單位:四川省維克奇生物科技有限公司

供應(yīng)電話:028-81700200/4008005713

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Related literature
Chicoric acid supplementation prevents systemic inflammation-induced memory impairment and amyloidogenesis via inhibition of NF-κB
Source:SCI:FASEB JOURNAL Author:Qian Liu Notes:影響因子:5.299
Reference description

The CA ($98%) was purchased from Weikeqi Biological Technology (Chengdu, Sichuan, China). Its chemical structure is

shown in Fig. 1A. LPS (L2630) and all other chemicals were the

purest grade available from Sigma-Aldrich


Comparison of chicoric acid, and its metabolites caffeic acid and caftaric acid: In vitro protection of biological macromolecules and inflammatory responses in BV2 microglial cells
Source:SCI:Food Science and Human Wellness Author:Qian Liu Notes:影響因子:5.154
Reference description

Chicoric acid, caffeic acid, and caftaric acid (purity ≥ 98%) were purchased from Weikeqi Biological Technology Co., Ltd. (Sichuan, China). Bovine serum albumin (BSA), 2,2-azobis (2-amidinopropane) dihydrochloride (AAPH), herring sperm DNA (hsDNA, D3159)

Chicoric acid improves neuron survival against inflammation by promoting mitochondrial function and energy metabolism
Source:SCI:Food & Function Author:Qian Liu Notes:影響因子:3.241
Reference description

Chicoric acid (purity ≥ 98%) was purchased from Weikeqi

Biological Technology Co., Ltd (Sichuan, China). The chemical

structure of CA is shown in Fig. 1A. Lipopolysaccharide (LPS),

3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide

(MTT), 2′,7′-dichlorofluorescin diacetate (DCFH-DA),


Chicoric acid supplementation ameliorates cognitive impairment induced by oxidative stress via promotion of antioxidant defense system
Source:SCI:RSC Advances Author:Yutang Wang Notes:影響因子:3.108
Reference description

The concentration of chicoric acid (purity ≥ 98%) (Fig. 1A), purchased from Weikeqi Biological Technology Co., Ltd (Sichuan, China), was 100 mg kg?1 for the in vivo experiments based on previous studies.35 Mice in the d-gal group and the d-gal + chicoric acid group were intraperitoneally injected (i.p.) with d-gal

Metabolism of chicoric acid by rat liver microsomes and bioactivity comparisons of chicoric acid and its metabolites
Source:SCI:Food & Function Author:Qian Liu Notes:影響因子:2.791
Reference description

Standards of chicoric acid, caffeic acid, and caftaric acid (purity ≥98%) were purchased from Weikeqi Biological Technology Co., Ltd (Sichuan, China). Rat liver microsomes were obtained from CHI Scientific, Inc. (Massachusetts, USA). Glucose-6-phosphate (G-6-P), G-6-P dehydrogenase (G-6-PD), β-nicotinamide adenine dinucleotide phosphate (NADP), 1,1-diphenyl-2-picrylhydrazyl radical 2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl (DPPH), 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS)

Pharmacokinetics, tissue distribution, and plasma protein binding study of chicoric acid by HPLC–MS/MS
Source:SCI:JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES Author:Yutang Wang Notes:影響因子:2.687
Reference description

Standards of chicoric acid, and ferulic acid (purity?≥98%) were purchased from Weikeqi Biological Technology Co., Ltd (Sichuan, China). Chromatographic grade methanol, ethyl acetate, and acetonitrile were purchased from Tedia Company Inc. (Fairfield, USA).

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